Oral antihistamine

The science: Over-the-counter oral antihistamine can soothe a rash that is swollen, red or itchy. Oral antihistamines are a good way to treat rashes because they work on the immune system and help to regulate the response to an allergen. They work systemically to soothe symptoms, Soliman says.

The catch: Same as before, be cautious of interference with other medication and note that some antihistamines can cause drowsiness.

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